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Event ID: 16003 Source: MSExchangeTransport

Level
Description
Microsoft Exchange couldn't retrieve the new Transport server configuration. Components will keep running with the existing configuration.

For more information see Help and Support Center at http://go.microsoft.com/fwlink/events.asp.
Comments
 
First you have a couple of event 1050 from source MSExchange Extensibility (the execution time of agent 'Journaling Agent' exceeded 300000 (milliseconds) while handling event OnRoutedMes). Then you have the event 16003 and after the event 4003 from source MSExchange Messaging Policies. In the mean time you have the queues backing up messages. In my case there were no issue at all different levels used by the Transport (OS NICLAN WAN AD DNS the server Account its group its SPN. Flushing the transport service force the Transport to create a new Instance and reset any locking elements.

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