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Event ID: 2125 Source: MSExchangeMTA

Source
Level
Description
Statistics for DBI call (DB Server) : file writes GATEWAY, reads 40, cache hits 254, misses %5.  Attribute %6, value number %7, Object ID: %8 (00000000 => N/A). Caller %12 [%9 %10 %11] (8)
Comments
 
As per Microsoft: "The Microsoft Exchange Server disk may be full or a disk error may have occurred. The message transfer agent (MTA) service will stop if the disk is full". See MSEX2K3DB for additional information about this event.
Two Microsoft articles seemed to apply: ME244035 and ME242944. Copying the Info*.cfg files as suggested by ME244035 corrected the issue in my case.

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