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Event ID: 3006 Source: WinDefend

Source
Level
Description
Microsoft Forefront Client Security Real-Time Protection agent has encountered an error when taking action on spyware or other potentially unwanted software.
Error Code: 0x80508022
Error description: To finish removing spyware and other potentially unwanted software, restart the computer.
Comments
 
According to TB643195, you only need to restart the affected computers.

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