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Event ID: 4007 Source: MSExchangeTransport

Level
Description
Message delivery to the host '<host>' failed while delivering to the remote domain '<domain>' for the following reason: <reason>.
Comments
 
This issue can occur if you use Cisco ASA firewall in a mail environment. See ME948803 for details.

As per Microsoft: "This Warning event is logged when Exchange cannot deliver a message to a remote host". See MSEX2K3DB for additional information about this event.

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