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Event ID: 9581 Source: MSExchangeIS

Source
Level
Description
Error code <error code> returned from virus scanner initialization routine. Virus scanner was not loaded.
Comments
 
As per Microsoft: "This Error event is typically logged in one of the following conditions:
1.When you are using antivirus software that is not compatible with Exchange Server 2003
2.When you have an antivirus program installed and the antivirus program is damaged".
See MSEX2K3DB for additional information about this event.
As per Microsoft: "This issue may occur if the computer that is running Exchange Server has an antivirus program installed that is not compatible with Exchange Server 2003. To resolve this issue, install a version of the antivirus program that is compatible with Exchange Server 2003". See ME839115 for more details.
From Microsoft:"This behavior occurs because your antivirus software is not operating correctly and prevents the Exchange 2000 Server Information Store service from starting." For more information about this error see ME319754 or ME316650.

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